Extended Data Fig. 9: Nuclei shape, and size in human blastocysts.
From: Live imaging of late-stage preimplantation human embryos reveals de novo mitotic errors
a, Schematic illustrating how embryo and nuclei size and shape were measured. b, Human embryo volume (blue) and anisotropy (orange), as well as average nuclear volume (blue) and anisotropy (orange), measured across developmental time from eight different embryos. “n” indicates the number of cells. c, Example images from different embryos highlighting changes in nuclear size in individual nuclei over time, particularly during periods of embryo collapse. Data from three independent experiments. Scale bar, 30 μm.
