Fig. 6: Assembled E. coli from a mock community does not match reference genomes.
From: Troubleshooting common errors in assemblies of long-read metagenomes
a, A pangenome analysis of the E. coli reference genome used in the Zymo mock community and the E. coli circular genome assembled by metaMDBG. Each layer corresponds to a genome, and the coloring represents the presence or absence of a gene cluster from each genome. The gene clusters are organized by the synteny of genes in the metaMDBG contig. b,c, Genome pairwise average nucleotide identity (b) and alignment coverage (c). d, Details of the long-read mapping over two genomic regions highlighted in a. These regions included genes not found in E. coli B1109 (closest reference genome by ANI metrics), but rather found in other E. coli genomes.
