Supplementary Figure 7: cDNM-enriched regions in the replication cohort. | Nature Genetics

Supplementary Figure 7: cDNM-enriched regions in the replication cohort.

From: Germline de novo mutation clusters arise during oocyte aging in genomic regions with high double-strand-break incidence

Supplementary Figure 7

Overview of regions enriched for maternal cluster mutations. X-axis and ideograms indicate chromosomal position. The red and blue histograms indicate the number of maternal cDNMs and paternal cDNMs identified in this study, respectively. The pale red and pale blue histograms indicate the number of maternal and paternal unclustered DNMs. The lowest track indicates normalized cSNP C>G score, which is predictive for maternal DNMs. (a) Full chromosome 16. (b) Full chromosome 8. (c) Region with increased maternal mutation rate on chromosome 9 (chr9: 0-10,000,000). (d) Region with increased maternal mutation rate on chromosome 2 (chr2: 0-10,000,000).

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