Supplementary Figure 12: Principal component analysis of sequencing-quality statistics.

The quality control variables are described in Supplementary Table 18. (a) First two principal components plotted against each other and colored by software version of data analysis pipeline. Spearman-correlation coefficient of PC1 and average coverage: −0.893. (b) Variance explained by principal components. (c) Principal components two and three plotted against each other and colored by estimated ancestry of sequenced individual.