Supplementary Figure 4: Gene ontology analysis from BCL11A ChIP–seq in HUDEP-2 cells. | Nature Genetics

Supplementary Figure 4: Gene ontology analysis from BCL11A ChIP–seq in HUDEP-2 cells.

From: Natural regulatory mutations elevate the fetal globin gene via disruption of BCL11A or ZBTB7A binding

Supplementary Figure 4

a,b, Gene ontology for the top 3,000 BCL11A ChIP–seq peaks analyzed with DAVID Bioinformatics Resources 6.7 and GOrilla, respectively. c,d, Gene ontology for the top 3,000 BCL11A ChIP–seq peaks located in promoters (–1,000 to +100 bp from the TSS) that do not contain the TGNCCA motif, analyzed by DAVID Bioinformatics Resources 6.7 and GOrilla, respectively. e,f, Gene ontology for the top 3,000 BCL11A ChIP–seq peaks located in promoters (–1,000 to +100 bp from the TSS) that do contain the TGNCCA motif, analyzed by DAVID Bioinformatics Resources 6.7 and GOrilla, respectively. Shown are the top 20 most significant GO terms for each analysis. The DAVID Bioinformatics Resources 6.7 and GOrilla analyses were performed on the peaks generated from n = 2 biologically independent replicates.

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