Supplementary Figure 7: Association of ecDNA-carrying primary tumors with time-to-secondary surgery.

a, Time to second surgery was compared between ecDNA-carrying primary tumors and non-carrying primary tumors. P-values were derived by the log-rank test in R’s survival package. Confidence intervals for the median survival were derived by the survfit function in R’s survival package. In cases where confidence intervals for median survival failed to be estimated, median survival was predicted.