Supplementary Figure 1: Comparison of DNA copy number and loss of heterozygosity.

Genome wide DNA copy number profiles. Left panel: Copy number increases (red) and decreases (blue) are plotted as a function of distance along the normal genome (vertical axis, divided into chromosomes). Right panel represents segmented B-allele-frequencies at heterozygous germline SNPs, which reflects patterns of loss of heterozygosity. Two cases with diploid but homozygous chromosome 10 are highlighted. See also Supplementary Figure 8.