Supplementary Figure 9: MaxCPP enrichment estimates are not sensitive to the maximum number of causal variants per locus modeled by CAVIAR. | Nature Genetics

Supplementary Figure 9: MaxCPP enrichment estimates are not sensitive to the maximum number of causal variants per locus modeled by CAVIAR.

From: Leveraging molecular quantitative trait loci to understand the genetic architecture of diseases and complex traits

Supplementary Figure 9: MaxCPP enrichment estimates are not sensitive to the maximum number of causal variants per locus modeled by CAVIAR.

We report MaxCPP enrichment estimates for each of 44 GTEx tissues with CAVIAR modeling either up to six or up to three causal variants per locus. We determined that results were not statistically different. The y axis is the enrichment meta-analyzed value, and error bars represent 95% confidence intervals. These values were computed by meta-analyzing 41 independent traits (n = 41 independent traits to derive the statistics). Numerical results are reported in Supplementary Table 37.

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