Supplementary Figure 8: Ingenuity pathway analysis of blood pressure genes.

Ingenuity pathway analysis for genes mapped to 357 sentinel SNPs at 274 known loci and genes mapped to all 901 loci. Sentinel gene mapping is compared to genes identified by extended LD (r2 > 0.8). Pathway enrichment is represented as –log P-value. (a) Canonical pathway enrichment. (b) Upstream regulator enrichment. (c) Disease and Biofunction enrichment.