Supplementary Figure 12: Effect of BMI adjustment on genetic correlation estimates between various traits and T2D. | Nature Genetics

Supplementary Figure 12: Effect of BMI adjustment on genetic correlation estimates between various traits and T2D.

From: Fine-mapping type 2 diabetes loci to single-variant resolution using high-density imputation and islet-specific epigenome maps

Supplementary Figure 12: Effect of BMI adjustment on genetic correlation estimates between various traits and T2D.

Genetic correlations (z-score) between range of metabolic and anthropometric traits and T2D without BMI adjustment (x-axis) and T2D with BMI adjustment (y-axis) as estimated using LD Score regression. The genetic correlation estimates are colour coded according to phenotypic area. Allelic direction of effect is aligned to increased T2D risk. Size of the circle denotes the significance level for the correlation.

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