Supplementary Figure 10: SCHLAP1 induces open chromatin changes but does not alter histone modifications. | Nature Genetics

Supplementary Figure 10: SCHLAP1 induces open chromatin changes but does not alter histone modifications.

From: SWI/SNF remains localized to chromatin in the presence of SCHLAP1

Supplementary Figure 10: SCHLAP1 induces open chromatin changes but does not alter histone modifications.The alternative text for this image may have been generated using AI.

a, Example loci representing open and closed chromatin regions from three independent replicate ATAC-seq experiments on two independent SCHLAP1 cell lines. b, Genomic loci associated with open, closed, and static sites. *P = 0.001, chi-squared test. c, The heatmap displays open chromatin, H3K4me3, H3K4me1, or H3K27ac signal in RWPE1;LACZ or RWPE;SCHLAP1 cells. Rows are ordered according to level of open chromatin signal. d, The heatmap shows the level of three SWI/SNF subunits present in RWPE1;SCHLAP1 cells at altered open chromatin sites. Order is the same as in c.

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