Supplementary Figure 3: Manhattan plots of univariate GWAMAs.
From: Multivariate genome-wide analyses of the well-being spectrum
The result of polygenic risk prediction based on univariate discovery GWAMA, N-weighted discovery GWAMA, or model averaging discovery GWAMA. The unit on the y-axis is the R-squared in percentage, obtained from a regression of the trait on the PRS, age, sex and 10 principle components. (a) life satisfaction, (b) positive affect, (c) neuroticism, (d) depressive symptoms. The x-axis represents the chromosomal position, and the y-axis represents the significance on a –log10 scale.” Sample size of the included traits are displayed in Supplementary Table 3. The top dashed line represents the significant threshold (p < 5 X 10−8)
