Supplementary Figure 14: Clonal analysis of BASCs after lung injuries.
From: Lung regeneration by multipotent stem cells residing at the bronchioalveolar-duct junction
(a) Immunostaining for GFP, YFP, RFP, Acetylated-tubulin on Sftpc-DreER;Scgb1a1-CreER;R26-Confetti2 mouse lung sections after naphthalene treatment. Arrowheads indicate YFP+Acetylated-tubulin+ cell or RFP+Acetylated-tubulin+ cells in naphthalene-induced lung. (b-e) Immunostaining for GFP, YFP, RFP, CC10, SPC or T1a on Sftpc-DreER;Scgb1a1-CreER;R26-Confetti2 mouse lung sections after naphthalene, vehicle or bleomycin treatment. Arrowheads indicates GFP/YFP+SPC+ cell in naphthalene-induced lung (b), GFP+SPC+ cell in vehicle-induced lung (c), RFP+CC10+ cell in bleomycin-induced lung (d) and RFP+T1a– cell in vehicle-treated lung (e). Scale bars, 100 µm. Each image is a representative of 4 individual samples.
