Supplementary Fig. 2: Design of microfluidic devices.
From: High-throughput single-cell ChIP-seq identifies heterogeneity of chromatin states in breast cancer
(a) Device used to compartmentalize cells in 45 pl droplets. (b) Device used to produce 9 pl droplets to make hydrogel beads. (c) Device used for compartmentalization of hydrogel beads in 100 pl droplets. (d) Device used to merge nucleosome-containing droplets with hydrogel barcoded bead- containing droplets. Potential and ground electrodes are indicated with the ‘+’ and the ‘-’ marks, respectively. Scale bars correspond to 2 mm.
