Supplementary Fig. 10: Identification of conserved cell types across Adamts19 genotypes. | Nature Genetics

Supplementary Fig. 10: Identification of conserved cell types across Adamts19 genotypes.

From: Loss of ADAMTS19 causes progressive non-syndromic heart valve disease

Supplementary Fig. 10

A) Dimensional reduction (UMAP) of single-cell transcriptomes integrated across Adamts19 genotypes reveals cardiac cell types for wildtype (+/+) and knockout cells (KO/KO) at E14.5. B) Dot plot of traditional markers for cardiac cell types alongside computationally identified markers from single-cell transcriptomics data. Expression is shown for cell types in both genotypes Adamts19+/+ (+/+) and Adamts19KO/KO (KO/KO). Color intensity represents relative expression and dot point size the percentage of cells expressing the marker.

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