Extended Data Fig. 4: RNA:DNA hybrids exhibit cell cycle-specific dynamics in hPSCs. | Nature Genetics

Extended Data Fig. 4: RNA:DNA hybrids exhibit cell cycle-specific dynamics in hPSCs.

From: N6-methyladenosine regulates the stability of RNA:DNA hybrids in human cells

Extended Data Fig. 4: RNA:DNA hybrids exhibit cell cycle-specific dynamics in hPSCs.

RNA:DNA hybrids exhibit cell cycle-specific dynamics in hPSCs. (a) The diagram illustrating gating of single hiPSCs using PI-Area and PI-Width signals (left panel) and DNA content frequency histogram (right panel) of a representative hiPSCs population used for cell cycle analysis. hPSCs at G0/G1, S and G2/M phases are marked. (b) The coverage plots of m6A DIP and S9.6 DRIP densities (CPK) in the intronic regions of the indicated genes. m6A and S9.6 peaks are marked with red and blue rectangles.

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