Extended Data Fig. 5: Differences in the fitness effect of CH mutations and the environment shape clonal dominance over an individual’s lifetime. | Nature Genetics

Extended Data Fig. 5: Differences in the fitness effect of CH mutations and the environment shape clonal dominance over an individual’s lifetime.

From: Cancer therapy shapes the fitness landscape of clonal hematopoiesis

Extended Data Fig. 5: Differences in the fitness effect of CH mutations and the environment shape clonal dominance over an individual’s lifetime.

Conceptual graph illustrating how associations between specific exposures and CH mutations may shape clonal dominance over an individual’s lifetime. AML, acute myeloid leukemia; cyclophosph, cyclophosphamide; MDS, myelodysplastic syndrome.

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