Fig. 6: dACE2 is induced by SARS-CoV-2 in human cell lines and organoid cultures. | Nature Genetics

Fig. 6: dACE2 is induced by SARS-CoV-2 in human cell lines and organoid cultures.

From: Interferons and viruses induce a novel truncated ACE2 isoform and not the full-length SARS-CoV-2 receptor

Fig. 6

a–d, Expression of ACE2, dACE2 and a control ISG IFIT1 in the colon cancer cell lines Caco-2 and T84 and the lung cancer cell line Calu3 (all in three to four biological replicates) (a) and colon and ileum organoid cultures from three donors (c), and the SARS-CoV-2 viral loads in the corresponding cells (b,d). The P values are for two-sided Student’s t-tests, unpaired tests for cell lines and paired tests for organoids. The results are presented with means and s.d.

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