Extended Data Fig. 2: Survival analyses of p53-SRSF1 PPI perturbing-mutations and p53 mutations alone. | Nature Genetics

Extended Data Fig. 2: Survival analyses of p53-SRSF1 PPI perturbing-mutations and p53 mutations alone.

From: Comprehensive characterization of protein–protein interactions perturbed by disease mutations

Extended Data Fig. 2: Survival analyses of p53-SRSF1 PPI perturbing-mutations and p53 mutations alone.The alt text for this image may have been generated using AI.

Three exemplary cancer types, including bladder urothelial carcinoma (BLCA), breast invasive carcinoma (BRCA), and colon adenocarcinoma (COAD), are illustrated. Survival analyses of p53-SRSF1 PPI perturbing-mutations across other cancer types/subtypes are provided in Supplementary Fig. 14. The p-value (P) was computed by log-rank test. All oncoPPI-predicted survival analyses for 33 cancer types/subtypes are freely available at the following website: https://mutanome.lerner.ccf.org/.

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