Extended Data Fig. 4: Intergenic anchors deleted in the mouse KO strains by CRISPR-Cas9. | Nature Genetics

Extended Data Fig. 4: Intergenic anchors deleted in the mouse KO strains by CRISPR-Cas9.

From: Chromatin interaction analyses elucidate the roles of PRC2-bound silencers in mouse development

Extended Data Fig. 4: Intergenic anchors deleted in the mouse KO strains by CRISPR-Cas9.

PRC2 interactions and binding profiles from 5 of the 6 KO regions (si-Δchr9 is shown in Fig. 3a). Selective genes connected by the KO regions through the PRC2 loops are labelled. Chromosome location (from top to bottom) are as follow; chr11:118,861,894-119,194,521, chr5:28,100,320-28,484,061, chr3:107,423,514-107,782,737, chr7:143,061,554-143,537,289 and chr2:18,568,747-19,024,016.

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