Extended Data Fig. 4: Genome-wide copy-number profiles of TCGA-LUAD and BM-LUAD.

a, Heatmap of copy-number profiles for samples from TCGA-LUAD (top) and BM-LUAD (bottom). Each row represents the copy-number profile of a tumor sample across chromosomes 1 to 22 and X. Red indicates copy-number gain; blue, loss. b, Frequencies of genome doubling events in TCGA-LUAD and BM-LUAD.