Extended Data Fig. 10: Later metastatic seeding is associated with higher genomic divergence in matched primary tumors. | Nature Genetics

Extended Data Fig. 10: Later metastatic seeding is associated with higher genomic divergence in matched primary tumors.

From: Multi-cancer analysis of clonality and the timing of systemic spread in paired primary tumors and metastases

Extended Data Fig. 10

a, The number of primary (P)-private clonal sSNVs and metastasis (M)-private clonal sSNVs in synchronous (distant and monoclonal, n = 41) and metachronous (distant and monoclonal, n = 80) metastases, respectively. b, The number of P-to-M altered sCNAs in synchronous and metachronous metastases, respectively; P-values, two-sided Wilcoxon Rank-Sum Test. Bar, median; box, 25th to 75th percentile (interquartile range, IQR); vertical line, data within 1.5 times the IQR.

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