Extended Data Fig. 3: Tests for casual effects of disease outcomes on risk factors. | Nature Genetics

Extended Data Fig. 3: Tests for casual effects of disease outcomes on risk factors.

From: Mendelian randomization accounting for correlated and uncorrelated pleiotropic effects using genome-wide summary statistics

Extended Data Fig. 3

Tests for casual effects of disease outcomes on mediators. Each cell summarizes the results of six methods for a pair of traits. In the left column of the cell, methods from bottom to top are CAUSE, IVW regression, and Egger regression. In the right column, methods from bottom to top are weighted median, weighted mode, and MR-PRESSO. Filled symbols indicate a nominally significant p < 0.05.

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