Extended Data Fig. 4: Workflow of a CAUSE analysis. | Nature Genetics

Extended Data Fig. 4: Workflow of a CAUSE analysis.

From: Mendelian randomization accounting for correlated and uncorrelated pleiotropic effects using genome-wide summary statistics

Extended Data Fig. 4

Dashed boxes represent input data. Each solid box is an analysis step completed by the given function in the cause R package. LD pruning can be parallelized over chromosomes. Text at the bottom of boxes indicates user provided parameters and their default values. All analyses presented are run with default parameters.

Back to article page