Extended Data Fig. 2: Trans-ethnic and ancestry-specific chromosome X Manhattan plots. | Nature Genetics

Extended Data Fig. 2: Trans-ethnic and ancestry-specific chromosome X Manhattan plots.

From: Discovery of 318 new risk loci for type 2 diabetes and related vascular outcomes among 1.4 million participants in a multi-ancestry meta-analysis

Extended Data Fig. 2

a–d, Each graph represents a Manhattan plot. The y-axis corresponds to –log10 (P) for association with T2D in the respective ancestral group (a, Europeans (69,869 T2D cases, 127,197 controls); b, African American (23,305 T2D cases, 30,140 controls); c, Hispanics (8,616 T2D cases, 11,829 controls); d, Asians (893 T2D cases, 1,560 controls)). The x-axis represents chromosomal position on chromosome X. The blue line corresponds with a significance threshold of P = 5.0 × 10−8. The red line corresponds with genome-wide significance (P = 5.0 × 10−8).

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