Extended Data Fig. 7: Analysis of pediatric neuroblastoma with cis-X.
From: Discovery of regulatory noncoding variants in individual cancer genomes by using cis-X
(a) Copy number variations identified in the four neuroblastoma cell lines. The blue and red colors represent the deletion and amplifications, respectively, identified in these cell lines. (b) Circos plot showing the cis-activating structural rearrangements identified in NBL cell lines by cis-X. The copy number alterations in each genome are shown in the inner track, with blue lines representing a copy number of 1 and red a copy number of three. The cis-activating structural variants are shown as links in the middle of the plot, with purple links representing inter-chromosome translocations and green for intra-chromosome translocations. The target genes activated by these rearrangements are labeled on the outer track of each plot.
