Extended Data Fig. 1: Transcription imbalance modeling.
From: Discovery of regulatory noncoding variants in individual cancer genomes by using cis-X
Cumulative distribution of transcription imbalance under binomial transcription model (dotted line), beta-binomial model as implemented in MBASED (solid line), balanced transcription model (dashed line) and experimentally observed data (dots). Different RNA-seq coverages (N = 10, 50 and 100) are shown separately.
