Extended Data Fig. 2: Chromatin changes after degradation of SMARCA4. | Nature Genetics

Extended Data Fig. 2: Chromatin changes after degradation of SMARCA4.

From: Acute BAF perturbation causes immediate changes in chromatin accessibility

Extended Data Fig. 2

a, Western blot analyses confirming the degradation of SMARCA4 upon dTAG47 treatment in HAP1 SMARCA4dTAG cells (cropped images). b, Principal component analysis (PCA) of the ATAC-seq time-course data. c, Volcano plots displaying the chromatin accessibility changes after SMARCA4 degradation compared to control for different treatment length. Significant changes (Padj < 0.01 and abs(log2(fold-change)) >1) are colored in red. d, Browser track examples for regions falling into the 5 different clusters.

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