Extended Data Fig. 9: Partitioned heritability enrichments for brain shape with respect to stage- and cell-type-specific brain organoid open chromatin.

S-LDSC coefficient Z-scores and heritability fold-enrichment for annotations corresponding to the indicated cell-type and differentiation day were computed as described in Methods. Regression lines represent the linear best fit with intercept and organoid differentiation day as dependent variable, and grey areas represent 95% confidence intervals. P-values are from a two-tailed F-test.