Extended Data Fig. 4: Effects of SPTBN1 variants on axonal growth.
From: Pathogenic SPTBN1 variants cause an autosomal dominant neurodevelopmental syndrome
a, Images of DIV8 βII-SpWT, βII-SpHet, βII-SpKO, and GFP-βIISp rescued βII-SpKO neurons transfected at DIV3 with mCherry. Staining with an antibody specific for AnkG was used to label the AIS (yellow arrowhead) and to identify axonal processes. Scale bar, 30 μm. Images are representative of three independent experiments.
