Fig. 6: MAZ-delimited chromatin boundary at the HoxA cluster corresponds to boundaries in skeletal patterning in vivo. | Nature Genetics

Fig. 6: MAZ-delimited chromatin boundary at the HoxA cluster corresponds to boundaries in skeletal patterning in vivo.

From: CRISPR and biochemical screens identify MAZ as a cofactor in CTCF-mediated insulation at Hox clusters

Fig. 6

a, Representative Alcian blue–Alizarin red staining of axial skeletons indicating homeotic transformation (C7-to-T1 transformation) in WT versus MAZ Hoxa5|6 mice at postnatal day 0.5. b, Bar plot demonstrating the percentage of pups (postnatal day 0.5) with the cervicothoracic transformation phenotype in MAZ Hoxa5|6 compared to WT. Raw numbers of mice are shown in blue (Supplementary Fig. 6 for genetic deletions).

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