Fig. 8: The effect of lncRNAs on transcriptional bursting.
From: Transcriptional kinetics and molecular functions of long noncoding RNAs
a, Scatterplots representing burst parameters with 95% CIs for Txnrd1, Gsta4 and Hoxb13 on siRNA-induced knockdown of lncRNAs. b, Scatterplots representing burst parameters with 95% CIs for Sox9 and Cdkn2a on siRNA-induced knockdown of lncRNAs. c, Scatterplots representing burst parameters with 95% CIs for Txnrd1, Gsta4 and Hoxb13 on siRNA-induced knockdown of lncRNAs (for 1 representative siRNA from a). Distribution of simulated cases (100 simulations) when expression was modulated by burst frequency or size is shown in blue and red, respectively. d, Scatterplots representing burst parameters with 95% CIs for Sox9 and Cdkn2a on siRNA-induced knockdown of lncRNAs (for 1 representative siRNA from b). Distribution of simulated cases (100 simulations) when expression was modulated by burst frequency or size is shown in blue and red, respectively. a–d, Colored by siRNA. c,d, P values represent a two-sided maximum likelihood ratio test.
