Extended Data Fig. 4: INDEL frequency and smoking dose.

a, INDEL frequency versus smoking pack-years across all individuals (n = 33). Each dot indicates the median value and the minimal and maximal range of INDEL frequency of individuals. b, INDEL frequency of different group of individuals according to the smoking pack-years, with boxes indicating median number and interquartile range of the never (n = 14), light (n = 6), moderate (n = 6), and heavy (n = 7) smoking group, respectively.