Extended Data Fig. 5: Effects of smoking cessation on mutation frequency.

Median number of SNV and INDEL frequency among former smokers (n = 7) and current smokers (n = 12). a, each data point indicates the median value and the minimal and maximal range of SNV frequency of 3-8 nuclei per subject. b, each data point indicates the median value and the minimal and maximal range of INDEL frequency of 3-8 nuclei per subject. P values were obtained by likelihood ratio tests using negative binomial mixed-effect model.