Extended Data Fig. 2: Independent validation of three meningioma DNA methylation groups.
From: Meningioma DNA methylation groups identify biological drivers and therapeutic vulnerabilities
a, K-means consensus clustering of meningioma DNA methylation profiles from the discovery (n = 200, UCSF) and validation (n = 365, HKU) cohorts. b, Sampling distributions of DNA methylation group fractions from the discovery cohort (n = 100 per DNA methylation group), with the observed DNA methylation group fractions from the validation cohort denoted in grey. Lines represent means, and error bars represent standard deviations. The observed fractions of each DNA methylation group from the validation cohort fall within the sampling distributions from the discovery cohort.
