Extended Data Fig. 3: Conditional association analyses for COVID-19 severity within the chr12q24.13 region in COVNET patients of European and African ancestries. | Nature Genetics

Extended Data Fig. 3: Conditional association analyses for COVID-19 severity within the chr12q24.13 region in COVNET patients of European and African ancestries.

From: Genetic regulation of OAS1 nonsense-mediated decay underlies association with COVID-19 hospitalization in patients of European and African ancestries

Extended Data Fig. 3: Conditional association analyses for COVID-19 severity within the chr12q24.13 region in COVNET patients of European and African ancestries.The alternative text for this image may have been generated using AI.

a, Genomic region and association results (P-values) for 79 genotyped or confidently imputed markers for hospitalized compared to nonhospitalized COVID-19 in patients of European and African ancestries. Presented results are for logistic regression analyses conditioning on markers indicated by red dots. b, rs1131454. c, rs10774671. d, rs2660. e, rs4766664. f, rs1131454, rs10774671, rs2660, and rs4766664 combined. The horizontal dotted line represents the P = 0.05 significance threshold. All association analyses were performed using logistic regression models, adjusting for sex, age, squared mean-centered age, and 20 PCs. Full conditional association results for individual variants are provided in Supplementary Table 2.

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