Extended Data Fig. 5: Linking cellular process programs to relevant diseases and traits in each of six tissues. | Nature Genetics

Extended Data Fig. 5: Linking cellular process programs to relevant diseases and traits in each of six tissues.

From: Identifying disease-critical cell types and cellular processes by integrating single-cell RNA-sequencing and human genetics

Extended Data Fig. 5: Linking cellular process programs to relevant diseases and traits in each of six tissues.

Magnitude (E-score, dot size) and significance (-log10(P-value), dot color) of the heritability enrichment of cellular process programs (columns; obtained by NMF) in each of seven tissues (label on top) for traits relevant in that tissue (rows) using the Roadmap∪ABC strategy for the corresponding tissue. Details for all traits analyzed are in Supplementary Table 2.

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