Extended Data Fig. 9: Analysis of disease-dependent programs using alternative Roadmap∪ABC enhancer-gene linking strategies. | Nature Genetics

Extended Data Fig. 9: Analysis of disease-dependent programs using alternative Roadmap∪ABC enhancer-gene linking strategies.

From: Identifying disease-critical cell types and cellular processes by integrating single-cell RNA-sequencing and human genetics

Extended Data Fig. 9: Analysis of disease-dependent programs using alternative Roadmap∪ABC enhancer-gene linking strategies.

Magnitude (E-score, dot size) and significance (-log10(P-value), dot color) of the heritability enrichment of disease-dependent programs (columns) in UC (colon cells) using Roadmap∪ABC-immune (a), asthma (lung cells) using Roadmap∪ABC-immune (b), and MS (brain cells) using Roadmap∪ABC-brain (c). Details for all traits analyzed are in Supplementary Table 2.

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