Extended Data Fig. 2: Standardized effect sizes of immune and brain cell type programs. | Nature Genetics

Extended Data Fig. 2: Standardized effect sizes of immune and brain cell type programs.

From: Identifying disease-critical cell types and cellular processes by integrating single-cell RNA-sequencing and human genetics

Extended Data Fig. 2: Standardized effect sizes of immune and brain cell type programs.

Standardized effect size (τ*) (dot size) and significance (-log10(P-value), dot color) of the heritability enrichment of immune (a,b) or brain (c) cell type programs (columns) for blood cell traits (a), immune disease traits (b), or neurological/psychological related traits (c), based on SNP annotations generated with the Roadmap∪ABC-immune (a,b) or Roadmap∪ABC-brain (c) enhancer-gene linking strategy. Numerical results are reported in Supplementary Data 1. Details for all traits analyzed are in Supplementary Table 2.

Back to article page