Extended Data Fig. 9: Overview of sequence patterns recognized by Nvwa. | Nature Genetics

Extended Data Fig. 9: Overview of sequence patterns recognized by Nvwa.

From: Deep learning of cross-species single-cell landscapes identifies conserved regulatory programs underlying cell types

Extended Data Fig. 9: Overview of sequence patterns recognized by Nvwa.

(a) Mean saliency scores show transcriptional start site and important information-rich region recognized by Nvwa. (b) Comparison of the first-layer convolution filters derived from feature map-based approaches and gradient-based TF-MoDISco on Drosophila-specific model. (c) Examples of known TFBS compared with the PWMs of Nvwa first-layer in humans, mice, zebrafish, Ciona, Drosophila, C. elegans, and planarians.

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