Extended Data Fig. 3: Characterization of candidate genes and regions of CNAs.
a, Number of variants previously reported in the COSMIC database. b, Number of variants for each consequence. c, Distribution of cancer cell fractions binned in four groups [1-0.75],]0.75-0.5],]0.5-0.25],]0.25-]. The number of variants represented in each boxplot is detailed in Supplementary Table 12. d, Number of variants occurring in protein domains including two types of protein domains: sites and regions, as defined in by Prot2HG39.e, Distribution of cancer cell fractions of recurrent CN gains (red) and CN losses (blue). All boxplots show the minimum and maximum values and interquartile range. The number of CNAs represented in each boxplot is detailed in Supplementary Table 6.
