Fig. 6: Schematic of the human airway GAIN.
From: A spatially resolved atlas of the human lung characterizes a gland-associated immune niche
Schematic of the GAIN showing immune cell recruitment and extravasation facilitated by venous endothelial cells and IR-Ven-Peri (immune recruiting venous perivascular cells) and signaling patterns between SMG epithelial cells, CD4 T cells, B naive/B memory cells and B plasma cells to attract immune cells and promote antigen-specific T cell-dependent and T cell-independent pathways, leading to IgA secretion at the SMG.
