Extended Data Fig. 9: FACS gating based UMAP annotation. | Nature Genetics

Extended Data Fig. 9: FACS gating based UMAP annotation.

From: Single-cell sortChIC identifies hierarchical chromatin dynamics during hematopoiesis

Extended Data Fig. 9

(a–c) UMAP of the combined sortChIC data with the position of a selection of FACS sorted cells highlighted. neutrophils, monocytes, and DCs are labeled in (a) pDCs in (b) and B and NK cells in (c). (d) Schematic illustrating how reference cell types are used to systematically assign the rest of the cells without FACS-defined cell type label. (e) Final UMAP of the bone marrow data across four histone marks after assigning cell types to one of the 14 cell types in the reference.

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