Extended Data Fig. 3: Characteristics of GOLDPlus genome-wide significant variants in GOLD ancestry-based cohorts. | Nature Genetics

Extended Data Fig. 3: Characteristics of GOLDPlus genome-wide significant variants in GOLD ancestry-based cohorts.

From: Genome-wide association meta-analysis identifies 17 loci associated with nonalcoholic fatty liver disease

Extended Data Fig. 3: Characteristics of GOLDPlus genome-wide significant variants in GOLD ancestry-based cohorts.The alternative text for this image may have been generated using AI.

For each variant, the characteristics are shown for the GOLD ancestry-based analysis including: associated gene, NAFLD increasing effect allele (EA), effect allele frequency (EAF), effect/beta and 95% confidence interval (CI), Cochran’s Q heterogeneity I2 metric (HetSq) and heterogeneity P-value (HetPVal), EA P-value (P), and sample size (N). Results are for meta-analysis of GOLD European ancestry (red), African ancestry (blue), Hispanic ancestry (green), Chinese ancestry (purple), and all ancestries pooled (black). The estimates of the effect sizes (Beta) and 95% confidence interval in bidirectional testing within each ancestry and for all the ancestries combined were shown in the forest plots. The data underlying these plots are provided as Source Data.

Source data

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