Extended Data Fig. 10: The RCMB56 amp1 ecDNA interacts with chromosomal gene loci.
From: Circular extrachromosomal DNA promotes tumor heterogeneity in high-risk medulloblastoma
(a) Interchromosomal chromatin interactions detected by FitHiC2 between amp1 and other chromosomes. Interactions mapping to a gene locus are labelled. (b) Interaction density map between segments of chr1 and chr3, rendered in Juicebox. Vertical stripes indicate increased contact density between the ecDNA and chr3 over background interactions between chr1 and chr3.
