Extended Data Fig. 2: Patient cohort survival by genomic amplification class.
From: Circular extrachromosomal DNA promotes tumor heterogeneity in high-risk medulloblastoma
Kaplan-Meier curves indicating (a) overall survival and (b) progression-free survival for n = 338 medulloblastoma patients, stratified by the amplifications present in the patient tumors. Patients with ecDNA amplification had significantly worse overall and progression-free survival compared to those with linear amplifications and compared to those without focal somatic copy number amplification (fSCNA). * p < 0.05; ** p < 0.005.
