Extended Data Fig. 6: An elevated number of de novo mutations at sites with observed SNVs. | Nature Genetics

Extended Data Fig. 6: An elevated number of de novo mutations at sites with observed SNVs.

From: A mutation rate model at the basepair resolution identifies the mutagenic effect of polymerase III transcription

Extended Data Fig. 6: An elevated number of de novo mutations at sites with observed SNVs.

Sites were divided into mutation rate bins for the three different models. De novo mutation rates were calculated from whole-genome family sequencing data. Horizontal bars represent 95% Poisson confidence intervals for the de novo mutation rate within each bin. Vertical bars represent 95% confidence intervals for the ratio of Poisson rates between SNV and non-SNV sites within each bin.

Back to article page