Extended Data Fig. 1: Effect of replication fork direction on the rate of rare synonymous SNVs. | Nature Genetics

Extended Data Fig. 1: Effect of replication fork direction on the rate of rare synonymous SNVs.

From: A mutation rate model at the basepair resolution identifies the mutagenic effect of polymerase III transcription

Extended Data Fig. 1: Effect of replication fork direction on the rate of rare synonymous SNVs.

Four contexts with strongest replication asymmetry. Mutation rate calculated for the regions with the strongest replication fork polarity (top quartile). Mutation rate is relative to the least mutable strand. Error bars show 95% confidence intervals for the ratio of two Poisson variables.

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