Extended Data Fig. 7: Multimodal analyses of tumor states demonstrate TGFβ signaling in MP6 tumors. | Nature Genetics

Extended Data Fig. 7: Multimodal analyses of tumor states demonstrate TGFβ signaling in MP6 tumors.

From: Multiomic analysis of cervical squamous cell carcinoma identifies cellular ecosystems with biological and clinical relevance

Extended Data Fig. 7: Multimodal analyses of tumor states demonstrate TGFβ signaling in MP6 tumors.

(a) Bar plot shows enriched pathways from GO BP, REACTOME and HALLMARK using DEGs of tumor MP6, MP7, MP3 and MP4/5 cells profiled by scRNA-seq. FDR q values are derived from clusterProfiler package. (b) Dot plot shows the expression of immune inhibitory molecules in MP6 and MP7 tumor cells profiled by scRNA-seq. (c) Bar plot displays enriched pathways from GO BP using DEGs of immune-rich (left) and immune-poor (right) ROIs profiled by spatial proteomics. FDR q values are derived from clusterProfiler package.

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