Extended Data Fig. 6: Agreement between SuSiE and FINEMAP PIPs; SuSiE-inf and FINEMAP-inf PIPs.
From: Improving fine-mapping by modeling infinitesimal effects
a-b. Density plots of PIPs from fine-mapping 10 UK Biobank traits at sample size N = 366 K. X-axis shows PIPs from running SuSiE (or SuSiE-inf), y-axis shows PIPs from running FINEMAP (or FINEMAP-inf). Only variants with PIP > = 0.1 for either method are shown on the plots. c. Number of high-PIP variants identified by SuSiE, SuSiE-inf, FINEMAP, FINEMAP-inf, minPIP, minPIP-inf, meanPIP and meanPIP-inf, where meanPIP(-inf) is defined as taking the average PIP between SuSiE and FINEMAP (resp. SuSiE-inf and FINEMAP-inf). Data aggregated across 10 UKBB traits fine-mapped at N = 366 K. Numerical results available in Supplementary Table 27.
